Further notes about the morphostasis concept – split files

(33) Class control

I am not sure if I have addressed this before (a quick search for class + control suggests not). This has become a topical subject for some theorists. My two-penn'orth on this is that we need to keep in mind the "purpose" that seems to have emerged on the reason for employing an adaptive immune system. It acts as a memory for inflammatory stimuli; the initiation and control of the adaptive immune system is "inflammocentric": inflammation triggers it into remembering the inflammatory or non-inflammatory milieu of previous peptide debris encounters (even the B-cell system requires Mhc+peptide permission to turn into plasma cell antibody factories). This acts as a memory and (contrast) amplifier for inflammation: damaging or safe is turned from shades of grey towards exaggerated "black or white". So, the obvious conclusion is this: it is inflammation that triggers the adaptive system into reproducing and amplifying its preferred initial (innate) response – inflammation retains command and control. Class control is handed down as an amplification of the appropriate class of innate response.